Single-chain multiple antigen-binding molecule, its...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 16/00 (2006.01) C07K 16/30 (2006.01) C07K 16/40 (2006.01) C07K 16/46 (2006.01) C12N 15/62 (2006.01) G01N 33/531 (2006.01)

Patent

CA 2268258

The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.

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