C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2571844
It is found out that a minus-strand RNA virus has an efficient tumor- suppressive effect even in the case of carrying no gene having a therapeutic effect. Thus, it is intended to provide an anticancer agent containing the minus-strand RNA virus; a process for producing an anticancer agent which comprises the step of mixing the minus-strand RNA virus with a pharmaceutically acceptable carrier; and a method of suppressing cancer which comprises the step of administering the minus-strand RNA virus to a cancerous tissue.
On a découvert qu'un virus ARN à brin négatif présente un effet de suppression tumorale efficace même dans le cas où il ne porte aucun gène à effet thérapeutique. Donc, la présente invention a trait à un agent anticancéreux contenant le virus ARN à brin négatif; à un procédé pour la production d'un agent anticancéreux comprenant l'étape de mélange du virus ARN à brin négatif avec un support pharmaceutiquement acceptable; et à un procédé pour la suppression du cancer comprenant l'étape d'administration du virus ARN à brin négatif à un tissu cancéreux
Hasegawa Mamoru
Kondo Haruhiko
Okano Shinji
Shibata Satoko
Sueishi Katsuo
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dnavec Research Inc.
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