Thiosemicarbazonic acid esters

C - Chemistry – Metallurgy – 07 – D

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C07D 277/54 (2006.01) A61K 31/425 (2006.01) C07D 277/60 (2006.01)

Patent

CA 2097482

4-19113/A Novel thiosemicarbazonic acid esters Abstract The invention relates to novel thiosemicarbazonic acid esters of formula I Image (I) wherein R1 and R5 are lower alkyl, lower alk-2-en-1-yl or lower alk-2-yn-1-yl, R2 and R3 independently of one another are hydrogen or lower alkyl or together are lower alkylidene, and R4 is lower alkyl, lower alkoxy, lower alk-2-en-1-yl, lower alk-2-yn-1-yl, aryl-lower alkyl, aryl-lower alkenyl or lower alkoxycarbonyl-lower alkyl, and to the salts and tautomeric compounds and double-bond isomers thereof, to processes for the preparation of the said compounds, to pharmaceutical compositions comprising them and to their use as active ingredients in medicaments.

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