Secreted alpha-helical protein-36

Details Secreted alpha-helical protein-36 Secreted alpha-helical protein-36

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 39/395 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2415095

The present invention relates to polynucleotide and polypeptide molecules for mammalian secreted alpha helical protein-36 (Zalpha36). The polypeptides, and polynucleotides encoding them, are hormonal and may be used to regulate the functioning of the immune system. The present invention also includes antibodies to the Zalpha36 polypeptides. The Zalpha36 protein can be used to stimulate the production of leukocytes and to inhibit the production of platelets.

L'invention concerne des molécules de polynucléotide et de polypeptide pour protéine-36 en hélice alpha sécrétée par des mammifères (Zalpha36). Les polypeptides et les polynucléotides les codant sont hormonaux et peuvent être utilisés pour régulariser le fonctionnement du système immunitaire. L'invention concerne également des anticorps aux polypeptides Zalpha36. La protéine Zalpha36 peut être utilisée pour stimuler la production de leucocytes et inhiber la production de thrombocytes.

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