Method for determination of platelets quality

G - Physics – 01 – N

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G01N 15/02 (2006.01) G01N 33/49 (2006.01)

Patent

CA 2517058

There is provided a method for assessing the quality of platelet concentrates for determining their suitability for transfusion. More specifically dynamic light scattering measurements of the samples containing platelets are obtained and parameters, such as hydrodynamic radius and relative number of platelet derived microparticles, are derived from these measurements that are indicative of platelet quality.

L'invention concerne une méthode d'évaluation de la qualité de concentrés de plaquettes pour déterminer leur pertinence pour la transfusion. Plus précisément, on obtient des mesures de diffusion dynamique de la lumière des échantillons contenant des plaquettes et on dérive des paramètres, comme le rayon hydrodynamique et le nombre relatif de microparticules dérivées des plaquettes, à partir des mesures qui sont indicatives de la qualité des plaquettes.

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