A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) A61K 31/185 (2006.01) A61K 33/00 (2006.01) A61K 33/18 (2006.01) A61K 33/20 (2006.01) A61K 45/06 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2435419
The invention concerns pharmaceutical compositions comprising (i) at least a halogenated composition and (ii) at least a N-halogenated derivative of at least a compound selected among zwitterion and/or amino acid compounds. The halogenated composition is advantageously an alkaline metal hypochlorite, and preferably sodium hypochlorite, and N-halogenated derivative is preferably a N-halogenated taurine derivative and particularly a N-haloamine taurine derivative and more preferably still N-chloramine taurine. The invention also concerns the preparation of said compositions and their use as very large spectrum antiseptic, anti-inflammatory agent and as immunity modulator, without stimulating myeloperoxidase activity.
La présente invention à pour objet des compositions pharmaceutiques comprenant (i) au moins un composé halogéné et (ii) au moins un dérivé N-halogéné d'au moins un composé choisi parmi les composés zwittérioniques et/ou les acides aminés. Le composé halogéné est avantageusement un hypochlorite de métal alcalin, et de préférence l'hypochlorite de sodium, et le dérivé N-halogéné est de préférence un dérivé N-halogène de la taurine et particulièrement une N- haloamine taurine et tout préférentiellement la N-chloramine taurine. L'invention concerne aussi la préparation desdites compositions et leur utilisation comme antiseptique à très large spectre, antiinflammatoire et comme modulateur de l'immunité, sans stimuler l'activité de la myéloperoxydase.
Gowling Lafleur Henderson Llp
Mainnemare Arnaud
LandOfFree
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