Pharmaceutical composition comprising an immunosuppressant...

A - Human Necessities – 61 – K

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A61K 31/435 (2006.01) A61K 31/436 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2521250

Synergistic combinations of a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro-33-desoxyascomycin and an emollient such as dimethicone, glycerol or isostearyl isostearate are provided, which are useful in particular in the treatment of dermatological or mucosal diseases such as dry skin or atopic or contact dermatitis.

L'invention concerne des complexes médicamenteux d'un immunomodulateur ou d'un immunodépresseur de lymphocyte T macrolide, tel que la 33-épichloro-33-désoxyascomycine et un émollient, tel que la diméthicone, le glycérol ou l'isostéaryl isostéarate, utiles notamment dans le traitement des maladies dermatologiques ou des muqueuses, telles que la peau sèche ou la dermatite atopique ou de contact.

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