Polymorphic crystal form of a...

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C - Chemistry, Metallurgy

07

D

C07D 215/26 (2006.01) A61K 31/4704 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2659144

New polymorphic crystal form of (R)-5-[2-(5,6-diethyl-indan-2-ylamino)-l-hydroxyethyl]-8- hydroxy-lH -quinolin-2-one maleate designated crystal form Qalpha that is useful in the treatment of inflammatory or obstructive airways diseases. A method for preparing crystal form Qalpha is also described.

L'invention concerne une nouvelle forme cristalline polymorphe du maléate de (R)-5-[2-(5,6-diéthyl-indan-2-ylamino)-1-hydroxyéthyl]-8-hydroxy-1H-quinolin-2-one, nommée forme cristalline Qalpha, ladite nouvelle forme cristalline étant utile pour le traitement de maladies inflammatoires ou obstructives des voies respiratoires. L'invention concerne également un procédé de préparation de la forme cristalline Qalpha.

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