A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2629545
An antibody or an antigen binding fragment thereof which binds to mammalian .alpha.7 subunit of a nicotinic acetylcholine receptor or its functional variant and which is an agonist of said receptor or variant. Pharmaceutical compositions comprising same. A method of treating a subject suffering from an inflammatory condition comprising administering to said subject an antibody or an antigen-binding fragment as described herein.
L~invention concerne un anticorps ou un fragment d~anticorps qui se lie à un antigène se liant à une sous-unité .alpha.7 d'un récepteur nicotinique de l~acétylcholine de mammifère ou à sa variante fonctionnelle, et qui est un agoniste dudit récepteur ou de sa variante ; des compositions pharmaceutiques qui comprennent ledit anticorps ; une méthode pour traiter un sujet souffrant d'un trouble inflammatoire et qui consiste à administrer audit sujet un anticorps ou un fragment qui se lie à un antigène comme décrit dans la présente.
Tracey Kevin J.
Yang Lihong
Gowling Lafleur Henderson Llp
The Feinstein Institute For Medical Research
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