Methods and compositions using immunomodulatory compounds...

A - Human Necessities – 61 – K

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Details

A61K 31/454 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/138 (2006.01) A61K 31/166 (2006.01) A61K 31/175 (2006.01) A61K 31/4188 (2006.01) A61K 31/4745 (2006.01) A61K 31/475 (2006.01) A61K 31/555 (2006.01) A61K 31/664 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2505128

Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable of ruse in methods of the invention are also disclosed.

La présente invention concerne des procédés pour traiter, prévenir et/ou maîtriser des cancers, des maladies et des troubles associés à ou caractérisés par une angiogenèse non souhaitée. Des procédés spécifiques consistent à administrer un composé immunomodulateur seul ou associé à un second ingrédient actif. Cette invention concerne également des procédés pour réduire ou supprimer des effets secondaires indésirables associés à une chimiothérapie, une radiothérapie, une hormonothérapie, une biothérapie ou une immunothérapie, qui consistent à administrer un composé immunomodulateur. En outre, cette invention concerne des compositions pharmaceutiques, des formes posologiques unitaires et des kits à utiliser dans le cadre des procédés de cette invention.

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