Morphinan derivatives with high oral bioavailability

Details Morphinan derivatives with high oral bioavailability Morphinan derivatives with high oral bioavailability

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61K 31/4748 (2006.01) A61P 25/32 (2006.01)

Patent

CA 2754984

The instant application relates to morphinan derivatives of formula I with enhanced oral bioavailability for the treatment of diseases associated with opioid receptor activity or blockade including alcohol and opiate addiction.

La présente invention porte sur des dérivés de morphinane représentés par la formule I, dont la biodisponibilité orale est améliorée pour le traitement de maladies associées à une activité ou à un blocage de récepteur opioïde, notamment l'addiction à l'alcool et à un opiacé.

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