Recombinant vaccines against caligid copepods (sea lice) and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61P 37/04 (2006.01) C07K 14/435 (2006.01)

Patent

CA 2575218

Molecular targets and vaccines against them in the treatment of sea lice infection of fish are provided, particularly caligid copepods. Vaccines targeted to L. salmonistrypsin are shown to reduce the quantity of sea lice present in challenged salmon from day 14 p.i. onward. Additional and novel molecular targets for vaccines are also provided.

L'invention concerne des cibles moléculaires et des vaccins contre celles-ci dans le traitement de l'infection due aux poux du poisson, notamment les copépodes caligides. Des vaccins ciblés sur L. salmonis trypsine permettent de réduire la quantité de poux du poisson présente dans le saumon testé à partir du 14è jour après l'infection. L'invention porte aussi sur des cibles moléculaires supplémentaires et nouvelles pour des vaccins.

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