Preparation of crystal form ii of clarithromycin

Details Preparation of crystal form ii of clarithromycin Preparation of crystal form ii of clarithromycin

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01)

Patent

CA 2261732

The present invention provides a process for the preparation of 6-O- methylerythromycin A Form II comprising converting erythromycin A to 6-O- methylerythromycin A and treating the 6-O-methylerythromycin A with a number of common organic solvents or mixtures of common organic solvents.

L'invention concerne un procédé permettant de fabriquer la forme II de la 6-O-méthylérythromycine A. Selon ce procédé, on convertit l'érythromycine A en 6-O-méthylérythromycine A, puis on traite cette dernière avec un certain nombre de solvants organiques communs ou de mélanges de solvants organiques communs.

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