Pharmaceutical compositions of rosuvastatin calcium

A - Human Necessities – 61 – K

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A61K 9/20 (2006.01) A61K 31/505 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2728539

This invention is related to pharmaceutical compositions of rosuvastatin or pharmaceutically acceptable salts thereof especially calcium salt with sodium carbonate anhydrous which has effects on dissoltion profiles in 0.1 N HCI medium provided that using of sodium carbonate anhydrous should be presence in the range of from about 0,5 % to about 2 % by weight.

Linvention concerne des compositions pharmaceutiques de rosuvastatine ou ses sels pharmaceutiquement acceptables, notamment le sel de calcium avec du carbonate de sodium anhydre qui a des effets sur les profils de dissolution dans un milieu HCl 0,1 N, à condition que lutilisation de carbonate de sodium anhydre ait lieu dans la plage allant denviron 0,5 % à environ 2 % en poids.

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