Dosage form for delivery of multiple drug forms

Details Dosage form for delivery of multiple drug forms Dosage form for delivery of multiple drug forms

A - Human Necessities

61

K

A61K 9/20 (2006.01)

Patent

CA 2565253

Disclosed are controlled release dosage forms and related methods including: (a) a micronized or liquid base form of a drug; (b) either a pharmaceutically acceptable salt form of the drug or starting materials that are capable of reacting to form a pharmaceutically acceptable salt form of the drug; (c) an upper gastrointestinal system pharmaceutically acceptable salt form releasing structure; and (d) a colonic system base form releasing structure.

La présente invention se rapporte à des formes posologiques à libération contrôlée et à des procédés associés. Ces formes posologiques contiennent: a) une forme de base micronisée ou liquide d'un médicament; b) soit une forme saline pharmaceutiquement acceptable du médicament soit des produits de départ qui sont capables de réagir pour produire une forme saline pharmaceutiquement acceptable du médicament; c) une structure libérant une forme saline pharmaceutiquement acceptable dans le système gastro-intestinal supérieur; et d) une structure libérant une forme basique dans le système du colon.

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