Recombinant vector

Details Recombinant vector Recombinant vector

C - Chemistry, Metallurgy

12

N

195/1.18, 195/1.

C12N 15/85 (2006.01) C07K 14/47 (2006.01) C07K 14/595 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/72 (2006.01) C12N 15/58 (2006.01) C12N 15/66 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2013453

ABSTRACT OF THE DISCLOSURE A recombinant vector suitable for industrially making an animal produce useful protein in its milk, which is con- constructed by extracting high molecular weight DNA from the bovine liver to prepare a chromosomal gene library, prepar- ing a synthetic DNA probe corresponding to the publicly known bovine .alpha.S1 casein chromosomal gene, screening a clone carrying bovine .alpha.S1 casein gene, confirming that the clone has a base sequence coincident with that of the publicly known bovine .alpha.S1 casein chromosomal gene, ligating human prourokinase cDNA with the promoter part and the intron 1 part of the gene, and then inserting the obtained plasmid into a suitable vector. A transgenic mouse prepared by using this recombinant vector secrete a considerable amount of human prourokinase as useful protein in its milk after delivery.

Affiliated with

Also associated with

Rating

Recombinant vector does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant vector, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant vector will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2023108