Multiple reaction monitoring mass spectrometer and method

H - Electricity – 01 – J

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H01J 49/34 (2006.01)

Patent

CA 2234754

A method of operating a mass spectrometer system in which ions are trapped in a first quadrupole mass spectrometer operated in an RF-only mode, at relatively high pressure, and all ions except parent ions are then removed therefrom using FNF or a similar technique. The ions are then fragmented in the first spectrometer, using radial or axial excitation or other desired method, and are then transferred to a resolving mass spectrometer for analysis.

Méthode pour faire fonctionner un système de spectromètre de masse, dans laquelle des ions sont piégés dans un premier spectromètre de masse quadripolaire fonctionnant uniquement en mode RF, à une pression relativement élevée; tous les ions, à l'exception des ions parents, sont alors retirés de là par la technique FNF ou une technique similaire. Les ions sont ensuite fragmentés dans le premier spectromètre, par excitation radiale ou axiale ou une autre méthode souhaitable, puis transférés à un spectromètre de masse pour analyse.

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