Treatment of hyperproliferative diseases with epidermal...

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) A01N 61/00 (2006.01) A61K 31/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2418083

A method is provided for treating a mammal with hyperproliferative disease stimulated by a ligand of epidermal growth factor receptor. The method includes administering an effective amount of an antagonists of a member of the EGF family of receptors. The method also includes administering an EGFR antagonist together with a chemotherpeutic agent, phototherpay, radiation therapy, or any combination thereof.

Cette invention concerne une méthode permettant de traiter un mammifère atteint d'une maladie hyperproliférative stimulée par un ligand de récepteur du facteur de croissance épidermique. La méthode consiste à administrer une dose efficace d'un antagoniste d'un membre des récepteurs de la famille des facteurs de croissance épidermiques. Elle consiste également à administrer un antagoniste du récepteur du facteur de croissance épidermique en association avec une chimiothérapie, une phytothérapie, une radiothérapie ou toute combinaison desdites thérapies.

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