Pyridazinone glucokinase activators

Details Pyridazinone glucokinase activators Pyridazinone glucokinase activators

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/501 (2006.01) A61P 3/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2720559

Provided herein are compounds of the formula (I), wherein X, Y, Q and R1 to R3 are defined in the specification, as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These com-pounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.

La présente invention concerne des composés représentés par la formule (I) dans laquelle X, Y, Q, R1, R2 et R3 sont tels que définis dans la description, ainsi que certains sels pharmaceutiquement acceptables de ces composés, les substituants étant tels que ceux énoncés dans la description. Ces composés, et les compositions pharmaceutiques les contenant, conviennent au traitement d'affections et de troubles du métabolisme tels que, par exemple, le diabète de type 2.

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