Stent-based delivery of statins to prevent restenosis

Details Stent-based delivery of statins to prevent restenosis Stent-based delivery of statins to prevent restenosis

A - Human Necessities

61

F

A61F 2/06 (2006.01) A61F 2/00 (2006.01) A61F 2/02 (2006.01)

Patent

CA 2445524

Restenosis of arteries after angioplasty in inhibited by implanting in the treated artery a stent (100) having the struts (102) coated with a composition including a statin (106) having anti-restenotic activity. Such statins may also be incorporated in a collagen or polymer matrix (106) that forms a coating covering the struts (102) and interstices (104) of the stent (100).

Selon cette invention, on inhibe la resténose des artères après angioplastie en implantant dans l'artère traitée un stent (100) dont les entretoises (102) sont recouvertes d'une composition comprenant une statine (106) à activité antiresténotique. Ces statines peuvent être également incorporées dans une matrice de collagène ou polymère (106) qui forme un revêtement recouvrant les entretoises (102) et les interstices (104) du stent (100).

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