Aminoguanidine assay and applications thereof

Details Aminoguanidine assay and applications thereof Aminoguanidine assay and applications thereof

G - Physics

01

N

150/14

G01N 33/68 (2006.01) G01N 33/53 (2006.01) G01N 33/66 (2006.01)

Patent

CA 2036631

ABSTRACT OF THE DISCLOSURE A method and associated materials including test kits for detecting and measuring the presence and amount of aminoguanidine and its analogs in biological samples is disclosed. Biological samples may include plasma, urine or tissue, and the present method may be used to determine the activity and effect of aminoguanidine and its analogs, particularly to the extent that such materials are useful as agents to prevent advanced glycosylation of proteins. The present invention extends to a new drug assay, suitable test kits, and to the assessment of kidney function and the potential to aid in the diagnosis of underlying pathologies where kidney dysfunction is a symptom.

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