Hydroxylamines and derivatives for the inhibition of...

A - Human Necessities – 61 – K

Patent

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A61K 31/445 (2006.01) A61K 31/421 (2006.01)

Patent

CA 2640738

Methods for the inhibition of complement activation, for the treatment of complement-mediated pathologies, and for the treatment of drusen-mediated pathologies are disclosed. The methods utilize hydroxylamine compounds and ester derivatives thereof, administered to subjects in effective amounts.

La présente invention concerne des procédés d'inhibition de l'activation du complément, pour le traitement de pathologies à médiation par un complément, ainsi que pour le traitement de pathologies à médiation par un corps colloïde. Les procédés font appel à des composés d'hydroxylamine et des dérivés esters de ceux-ci, administrés à des sujets en des quantités efficaces.

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