Diagnosis of coronary artery spasm-associated diseases

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2236809

The present invention relates to a process for screening for a gene involving a coronary artery spasm-associated disease, which comprises detecting the presence of the relevant nucleotide substituents in the endothelial nitric oxide synthase (eNOS) gene. The present invention provides the ready diagnosis of a coronary artery spasm-associated disease such as angina, which cannot be conveniently screened by the conventional methods.

Méthode de recherche des gènes de maladies associées au spasmes coronariens, consistant à évaluer la survenance de la substitution d'un nucléotide spécifique dans un gène de synthase de monoxide d'azote (eNOS) endothélial. Cette méthode facilite le diagnostic de maladies associées aux spasmes coronariens, telles que l'angine de poitrine à spasmes coronariens, qui ne peut être détectée facilement par les méthodes actuelles.

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