Fragment of l. lactis plasmid conferring antiphage activity...

Details Fragment of l. lactis plasmid conferring antiphage activity... Fragment of l. lactis plasmid conferring antiphage activity...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07K 14/315 (2006.01) C12N 1/21 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2441633

The present invention relates to a 2227-bp DNA fragment that confers antiphage activity. Two proteins encoded by this DNA sequence are responsible for the phage resistance phenotype. When introduced in Lactococcus lactis phage- sensitive strain, this DNA fragment aborts infection of phages of the 936 and P335 species.

L'invention concerne un fragment d'ADN 2227-bp conférant une activité antiphagique. Deux protéines codées par cette séquence d'ADN sont responsables du phénotype de résistances aux phages. Lorsque l'on introduit ce fragment d'ADN dans une souche de Lactococcus lactis sensible aux phages, celui-ci bloque l'infection des espèces 936 et P335 par les phages.

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