Intestinal alkaline phosphatase modulators and uses thereof

Details Intestinal alkaline phosphatase modulators and uses thereof Intestinal alkaline phosphatase modulators and uses thereof

A - Human Necessities

61

K

A61K 31/4162 (2006.01) A61K 31/415 (2006.01) A61K 31/4196 (2006.01) A61K 31/53 (2006.01) A61P 1/12 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2723424

Disclosed are modulators, i.e., activators and inhibitors, of Intestinal Alkaline Phosphatase (IAP). Also disclosed are methods for treating bacterial infections of the intestinal tract and methods for maintaining the health of the intestinal tract using IAP activators. Further disclosed are methods to assist in weight gain of emaciated patients and those having reduced or negligible fat absorption using IAP inhibitors.

L'invention porte sur des modulateurs, à savoir des activateurs et des inhibiteurs de la phosphatase alcaline intestinale (IAP). L'invention porte également sur des procédés de traitement des infections bactériennes du tractus intestinal et sur des procédés pour maintenir la santé du tractus intestinal à l'aide d'activateurs d'IAP. L'invention porte en outre sur des procédés pour aider au gain de poids de patients émaciés et de ceux ayant une absorption de graisses réduite ou négligeable à l'aide d'inhibiteurs d'IAP.

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