Prevention and treatment of gastrointestinal and bladder...

Details Prevention and treatment of gastrointestinal and bladder... Prevention and treatment of gastrointestinal and bladder...

A - Human Necessities

61

K

A61K 31/59 (2006.01)

Patent

CA 2622470

The present invention relates to a method for preventing, treating, or ameliorating gastrointestinal and bladder disorders in a patient receiving a chemotherapy or radiation therapy comprising administering to the patient a therapeutically effective amount of active vitamin D compound or a mimic thereof. According to the invention, the active vitamin D compound or a mimic thereof may be administered by high dose pulse administration so that high doses of the active vitamin D compound or a mimic thereof can be administered to an animal without inducing severe symptomatic hypercalcemia.

L'invention porte sur des méthodes de prévention, traitement ou amélioration des troubles gastro-intestinaux et de la vessie chez un patient traité par chimiothérapie ou radiothérapie consistant à lui administrer une dose à effet thérapeutique d'un composé actif de vitamine D ou de son mimétique. Un tel composé peut s'administrer par succession de fortes doses à un animal sans induire d'hypercalcémie symptomatique sévère.

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