Therapeutic polyanhydride compounds for drug delivery

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01)

Patent

CA 2417388

Polyanhydrides which link low molecular weight drugs containing a carboxylic acid group and an amine, thiol, alcohol or phenol group within their structure into polymeric drug delivery systems are provided. Also provided are methods of producing polymeric drug delivery systems via these polyanhydride linkers as well as methods of administering low molecular weight drugs to a host via the polymeric drug delivery systems.

L'invention concerne des polyanhydrides qui lient des médicaments de faible poids moléculaire contenant un groupe acide carboxylique et un groupe amine, thiol, alcool ou phénol dans leur structure à des systèmes d'administration de médicaments polymériques. L'invention concerne également des procédés de production de systèmes d'administration de médicaments polymériques grâce à ces lieurs polyanhydrides ainsi que des procédés d'administration de médicaments de faible poids moléculaire à un hôte au moyen de systèmes d'administration de médicaments polymériques.

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