Buccal and/or sublingual therapeutic formulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/32 (2006.01) A61K 47/40 (2006.01)

Patent

CA 2761538

A buccal and/or sublingual formulation comprising one or more active compounds; and a buccal matrix which re-leases the active compounds at a predetermined rate for transport across the buccal and/or sublingual membranes, wherein the rate of release of the active compounds is either (A) the same or substantially the same rate at which the active compounds are trans-ported across the buccal and/or sublingual membranes; or (B) a rate which releases the active compounds over an extended period as required by the therapeutic affect or treatment window for those active compounds.

La présente invention concerne une formulation buccale et/ou sublinguale comprenant un ou plusieurs composés actifs; et une matrice buccale qui libère les composés actifs à un taux prédéterminé pour le transport à travers les membranes buccale et/ou sublinguale, où le taux de libération des composés actifs est (A) un taux identique ou sensiblement identique auquel les composés actifs sont transportés à travers les membranes buccale et/ou sublinguale; ou (B) un taux qui libère les composés actifs pendant une période prolongée comme requis par la fenêtre d'effet thérapeutique ou de traitement pour ces composés actifs.

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