Use of a lacrophyl preparation in eye-drops containing...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 47/46 (2006.01)

Patent

CA 2407794

The invention refers to the use of a lacrophyl preparation containing lysozyme, tris(hydroxymethyl)aminomethane, if desired other lacrophyl components, preferably ascorbic acid and/or citric acid and/or ethylenediamine- tetraacetic acid, in the rest distilled water for the dissolution of an active substance being insoluble or only slightly soluble in water or physiological saline, for preparing eye-drops, and/or in case of eye-drops containing an active substance to adjust optionally an active substance medium appropriate to the composition of the native tear and for the microbiological protection of the medium.

L'invention concerne l'utilisation d'une préparation lacrophylique contenant un lysozyme, un tris(hydroxyméthyl)aminométhane, et le cas échéant, d'autres composants lacrophyliques, de préférence de l'acide ascorbique et/ou de l'acide citrique et/ou de l'acide éthylènediamine-tétraacétique, le reste étant constitué d'eau distillée en vue de la dissolution d'une substance active insoluble ou faiblement soluble dans l'eau ou toute autre solution physiologique saline, pour la préparation de gouttes ophtalmiques, et/ou dans le cas des gouttes ophtalmiques contenant une substance active, pour le réglage optique d'un milieu du type substance active approprié à la composition de la larme naturelle et la protection microbiologique dudit milieu.

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