Multilayered transmucosal therapeutic system

A - Human Necessities – 61 – K

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Details

A61K 9/00 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2502349

The invention relates to a film-type therapeutic system (1) comprising at least two interconnected layers, for the transmucosal administration of active ingredients. Said system comprises a layer (2) which is mucoadhesive in an aqueous environment, and a single-layer or multi-layer rear layer (3). At least one of said layers contains active ingredients, and the cited mucoadhesive layer (2) is capable of swelling in aqueous media, but is insoluble or only slightly soluble.

La présente invention concerne un système thérapeutique (1) sous forme de film, qui comprend au moins deux couches reliées l'une à l'autre et qui est conçu pour assurer une administration de substances actives par voie transmuqueuse. Ce système thérapeutique présente une couche (2) qui est mucoadhésive dans un environnement aqueux et une couche arrière (3) qui comprend une ou plusieurs couches. Au moins une de ces couches comprend des substances actives. Ladite couche mucoadhésive (2) peut gonfler dans des milieux aqueux, mais y est insoluble ou peu soluble.

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