Certain bridged 4-phenyl-2-aminomethylimidazoles; new...

Details Certain bridged 4-phenyl-2-aminomethylimidazoles; new... Certain bridged 4-phenyl-2-aminomethylimidazoles; new...

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 235/02 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01)

Patent

CA 2213197

Disclosed are compounds encompassed by general formula (I), wherein, A represents ethenylene, or A represents -X-CH2-; where X is carbon or oxygen, provided that when X is oxygen, the oxygen is adjacent the 6-membered ring; R1, R2, R3 and R4 are inorganic or organic substituents; and R5 and R6 are optionally substituted organic substituents; or NR5R6 represents a carbocyclic or heterocyclic six-membered ring optionally substituted with various organic or inorganic groups, which compounds can be used in the treatment of neuropsychological disorders.

La présente invention concerne des composés représentés par la formule générale (I). Dans cette formule générale, A représente l'éthénylène ou -X-CH¿2?-, X représente un carbone ou un oxygène dans la mesure où, lorsque X représente oxygène, l'oxygène est adjacent au noyau à 6 éléments, R¿1?, R¿2?, R¿3? et R¿4? sont des substituants non organiques ou organiques, et R¿5? et R¿6? sont des substituants organiques éventuellement substitués, ou bien NR¿5?R¿6? représente un noyau carbocyclique ou hétérocyclique à six éléments éventuellement substitué avec divers groupes organiques ou inorganiques. Ces composés conviennent particulièrement au traitement de troubles neuropsychologiques.

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