Formulations and methods of delivery of intact tocopheryl...

Details Formulations and methods of delivery of intact tocopheryl... Formulations and methods of delivery of intact tocopheryl...

A - Human Necessities

61

K

A61K 31/355 (2006.01) A61K 9/00 (2006.01) A61K 47/10 (2006.01) A61K 47/20 (2006.01) A61K 47/44 (2006.01) A61M 31/00 (2006.01) A61M 37/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2428711

Several formulations and methods of delivering anti-neoplastic tocopherol succinate to human subjects through transdermal and transmucosal routes to preserve its intactness are disclosed. Pharmaceutically acceptable carriers such as dimethyl sulfoxide, almond oil and water are used to process tocopherol succinate at different temperatures prior to applications. By administering tocopherol succinate in this manner, the molecular form of the tocopherol succinate is preserved, resulting in enhanced efficacy of the anti-neoplastic function in human. By using the formulations and delivery methods of the invention as sole treatment. several human cancer cases had been treated successfully in a relatively short period of time.

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