Agent for prophylaxis and treatment of liver disease

Details Agent for prophylaxis and treatment of liver disease Agent for prophylaxis and treatment of liver disease

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/16 (2006.01) A61K 31/437 (2006.01) A61K 31/4409 (2006.01) A61K 31/445 (2006.01) A61P 1/16 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 213/75 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2369560

Preventives/remedies for liver diseases which contain compounds having an Rho kinase inhibitory activity; and liver astrocyte activation inhibitors. Because of having excellent effects of inhibiting the activation of liver astrocytes, preventing the fibrosis of liver tissues, etc., compounds having an Rho kinase inhibitory activity (for example, (+)- trans-4-(1-aminoethyl)-1-(4- pyridylcarbamoyl) cyclohexane) are useful in preventing and treating various liver diseases such as hepatitis, hepatic fibrosis, liver cirrhosis and liver cancer.

La présente invention concerne des médicaments destinés à soigner et à prévenir les maladies du foie. Ces médicaments contiennent des composés ayant une activité inhibitrice de la Rho kinase, et des inhibiteurs d'activation d'astrocytes du foie. Du fait de leur excellents effets inhibiteurs de l'activation des astrocytes du foie, de leurs effets préventifs sur la cirrhose du foie, etc., les composés ayant une activité inhibitrice de la rho kinase (par exemple (+)-trans-4-(1-aminoéthyle) -1-(pyridylcarbomoyl) cyclohexane) conviennent pour soigner et prévenir diverses maladies du foie telles que l'hépatite, la cirrhose hépatique, la cirrhose du foie et le cancer du foie.

Affiliated with

Also associated with

Rating

Agent for prophylaxis and treatment of liver disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Agent for prophylaxis and treatment of liver disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Agent for prophylaxis and treatment of liver disease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2037926