Substituted felbamate derived compounds

Details Substituted felbamate derived compounds Substituted felbamate derived compounds

A - Human Necessities

61

P

A61P 25/00 (2006.01) A61K 31/27 (2006.01) A61K 31/38 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61P 27/06 (2006.01) C07C 205/00 (2006.01) C07C 271/12 (2006.01) C07D 213/02 (2006.01) C07D 213/30 (2006.01) C07D 233/54 (2006.01) C07D 239/02 (2006.01) C07D 239/26 (2006.01) C07D 241/02 (2006.01) C07D 241/12 (2006.01) C07D 263/04 (2006.01) C07D 263/24 (2006.01) C07D 263/30 (2006.01) C07D 263/32 (

Patent

CA 2427058

The present invention relates to novel felbamate derivatives and their use to threat neurological diseases such as epilepsy and neuropathic pain, and to treat tissue damage resulting form ischemic events. The felbamate derivatives are modified to prevent the formation of metabolites that are believed responsible for the toxicity associated with felbamate therapy.

L'invention concerne des nouveaux dérivés de felbamate et l'utilisation de ceux-ci dans le traitement de maladies neurologiques, telles que l'épilepsie et les douleurs neuropathiques, ainsi que dans le traitement de lésions tissulaires engendrées par des événements ischémiques. Les dérivés de felbamate sont modifiés de manière à prévenir la formation de métabolites tenues pour responsables de la toxicité associée à une thérapie au felbamate.

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