Preparation and utility of substituted quinazoline compounds...

Details Preparation and utility of substituted quinazoline compounds... Preparation and utility of substituted quinazoline compounds...

C - Chemistry, Metallurgy

07

D

C07D 405/14 (2006.01) A61K 31/517 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2660659

The present disclosure is directed to modulators of alpha-adrenergic receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the use of such compounds for the treatment and/or management of hypertension, cardiac failure, prostatitis, and benign prostatic hyperplasia, and any other condition in which it is beneficial to modulate an alpha-adrenergic receptor.

La présente invention concerne des modulateurs de récepteurs alpha-adrénergiques et certains de leurs sels et promédicaments pharmaceutiquement admis, leur synthèse, et l'utilisation de tels composés pour le traitement et/ou la gestion de l'hypertension, de l'insuffisance cardiaque, de la prostatite, de l'hyperplasie prostatique bénigne, et de tout autre état dans lequel il est bénéfique de moduler un récepteur alpha-adrénergique.

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