2-cyclopropyl-thiazole derivatives

Details 2-cyclopropyl-thiazole derivatives 2-cyclopropyl-thiazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01)

Patent

CA 2685743

The invention relates to selected 2-cyclopropyl-thiazole derivatives of the formula (I) wherein B, Y and R1 are as described in the description; to salts and especially pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.

L'invention porte sur des dérivés sélectionnés de 2-cyclopropyl-thiazole, représentés par la formule (I) dans laquelle B, Y et R1 sont tels que décrits dans la description ; sur des sels et notamment des sels pharmaceutiquement acceptables de ceux-ci, et sur l'utilisation de tels composés comme médicaments, notamment en tant qu'antagonistes des récepteurs de l'orexine.

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