A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2529798
Materials and methods for treating hepatocellular carcinoma in a mammal are disclosed. The methods comprise administering to a mammal a composition comprising a therapeutically effective amount of a zvegf3 antagonist in combination with a pharmaceutically acceptable delivery vehicle. Zvegf'3 antagonists include anti-zvegf3 antibodies, mitogenically inactive receptor- binding zvegf3 variant polypeptides, and inhibitory polynucleotides.
L'invention concerne des produits et des procédés de traitement de carcinome hépatocellulaire chez un mammifère. Les procédés comprennent l'administration, à un mammifère, d'une composition comprenant une quantité thérapeutiquement efficace d'un antagoniste de zvegf3, en combinaison avec un véhicule d'administration pharmaceutiquement acceptable. Des antagonistes de zvegf3 comprennent des anticorps anti-zvegf3, des polypeptides variants de zvegf3, à liaison avec un récepteur, mitogéniquement inactif et des polynucléotides inhibiteurs.
Osler Hoskin & Harcourt Llp
Zymogenetics Inc.
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