C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 279/18 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/27 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 51/00 (2006.01) C07C 279/24 (2006.01) C07C 317/44 (2006.01) C07C 323/62 (2006.01) C07D 207/337 (2006.01) C07D 213/58 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) G01N 33/60 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2235937
The invention relates to novel amino acid derivatives of general formula (I), in which R, U, V, Y, n, m and R1-R3 have the definitions shown in claim 1, and to their tautomers, diastomers, enantiomers, mixtures and salts, in particular their physiologically tolerable salts with inorganic or organic acids or bases, which have useful pharmacological properties, in particular selective NPY-antagonistic properties. Also disclosed are medicaments containing these compounds, their use and methods of producing them.
L'invention concerne de nouveaux dérivés d'acides aminés de la formule générale (I) où R, U, V, Y, n, m et R?1¿ à R?3¿ ont la signification donnée dans la revendication 1. L'invention concerne également leurs tautomères, leurs diastéréomères, leurs énantiomères, leurs mélanges et leurs sels, notamment leurs sels physiologiquement tolérables avec des acides ou bases inorganiques ou organiques qui présentent de précieuses propriétés pharmacologiques, notamment des propriétés antagonistes de NPY. L'invention concerne par ailleurs des médicaments contenant ces composés, leur utilisation et leur procédé de production.
Doods Henri
Eberlein Wolfgang
Engel Wolfhard
Rudolf Klaus
Wieland Heike-Andrea
Dr. Karl Thomae Gmbh
Fetherstonhaugh & Co.
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