Synthesis of acyclic nucleoside derivatives

Details Synthesis of acyclic nucleoside derivatives Synthesis of acyclic nucleoside derivatives

C - Chemistry, Metallurgy

07

C

C07C 309/73 (2006.01) C07C 303/30 (2006.01)

Patent

CA 2572577

Methods and novel intermediates for the preparation of acyclic nucleoside derivatives of formula (I) where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a -C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.

Divulgation de méthodes et de nouveaux intermédiaires pour la préparation de dérivés d'un nucléoside acyclique de formule (I) dans laquelle R1 ou R2 est un groupe acyle d'acide aminé et l'autre est un groupe -C(O)C3-C21 saturé ou mono-insaturé, pouvant être substitué avec un alkyle, et R3 est OH ou H. Divulgation aussi d'un sel acceptable en pharmacie.

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