Polypeptide comprising cell adhesion motif, t cell epitope...

Details Polypeptide comprising cell adhesion motif, t cell epitope... Polypeptide comprising cell adhesion motif, t cell epitope...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 39/39 (2006.01) A61P 37/02 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2734606

It is intended to provide polypeptide capable of inducing the potentiation of antibody production when transmucosally administered without resort to any immune adjuvants, a composition containing the polypeptide and use thereof. These objects can be achieved by establishing a polypeptide which is obtained by bonding the amino acid sequence of the adhesion motif of a cell adhesion molecule to a polypeptide comprising a peptide consisting of the amino acid sequence of a multi-agretope type T cell epitope in its amino-terminal side and the amino acid sequence of a B cell epitope in its carboxyl-terminal side while having a linker peptide between these amino acid sequences, and providing a composition containing the polypeptide and use thereof.

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