Semi-synthetic process for the preparation of taxane...

Details Semi-synthetic process for the preparation of taxane... Semi-synthetic process for the preparation of taxane...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01)

Patent

CA 2672911

This invention relates to an improved semi-synthetic process for the preparation of taxane derivatives like paclitaxel, docetaxel, canadensol and its derivatives, the process, which has shorten reaction route, simple procedure, high yield and low materials cost, therefore facilitates the commercial manufacture of these derivatives.

L'invention concerne un procédé de semi-synthèse amélioré permettant de préparer des dérivés de taxane tels que le paclitaxel, le docétaxel, le canadensol et leurs dérivés. Ce procédé, à voie de réaction raccourcie, faisant appel à une procédure simple, à haut rendement et à faible coût de matières, facilite ainsi la fabrication commerciale de ces dérivés.

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