Substituted pyrazinone amides

Details Substituted pyrazinone amides Substituted pyrazinone amides

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4965 (2006.01) A61P 3/10 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2748587

The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. The variables R1, R2, R3 and R4 are as described herein.

La présente invention concerne des composés de Formule (I) qui agissent en tant qu'activateurs de glucokinase ; des compositions pharmaceutiques les incluant ; et des méthodes de traitement de pathologies, de troubles ou d'états pathologiques faisant intervenir la glucokinase. Les variables R1, R2, R3 et R4 sont telles que décrites dans la présente invention.

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