Mass spectrometer

H - Electricity – 01 – J

Patent

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H01J 49/00 (2006.01)

Patent

CA 2564279

A mass spectrometer and method of mass spectrometry are disclosed wherein two separate samples are mass analysed and then the relative intensity, concentration or expression level of one or more components, molecules or analytes in a first sample is quantitated relative to the intensity, concentration or expression level of one or more components, molecules or analytes in a second sample. The relative quantitation is performed probabilistically without the need to resort to using internal calibrants.

L'invention concerne un spectromètre de masse et une méthode de spectrométrie de masse dans lesquels deux échantillons séparés sont analysés par spectrométrie de masse, puis l'intensité, la concentration ou le niveau d'expression relatifs d'au moins un constituant, une molécule ou un analyte d'un premier échantillon est quantifié par rapport à l'intensité, la concentration ou le niveau d'expression d'au moins un constituant, une molécule ou un analyte d'un second échantillon. Cette quantification relative s'effectue de manière probabiliste, sans qu'il soit nécessaire d'avoir recours à l'utilisation de calibrateurs internes.

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