Production of oligodendrocytes from placenta-derived stem cells

Details Production of oligodendrocytes from placenta-derived stem cells Production of oligodendrocytes from placenta-derived stem cells

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61K 35/12 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2624916

The present invention provides methods and compositions for the production of glial cells and oligodendrocytes from placenta stem cells. The invention further provides for the use of these glia and oligodendrocytes in the treatment of, and intervention in, for example, trauma, ischemia and degenerative disorders of the central nervous system (CNS), particularly in the treatment of demyelinating diseases such as multiple sclerosis.

La présente invention concerne des procédés et des compositions pour produire des cellules gliales et des oligodendrocytes à partir de cellules souches placentaires. L'invention a également pour objet l'utilisation de cette névroglie et d'oligodendrocytes dans le cadre du traitement, et de l'intervention dans, par exemple, le traumatisme, l'ischémie et les troubles de dégénérescence du système nerveux central (central nervous system / CNS), en particulier dans le cadre du traitement de maladies de démyélinisation telles que la sclérose en plaques.

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