Vegf-specific antagonists for adjuvant and neoadjuvant...

A - Human Necessities – 61 – K

Patent

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A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 38/43 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2671734

Disclosed herein are methods of treating benign, pre-cancerous, or non- metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating a subject at risk of developing benign, pre-cancerous, or non- metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating or preventing recurrence of a tumor using an anti-VEGF-specific antagonist as well as use of VEGF-specific antagonists in neoadjuvant and adjuvant cancer therapy.

L'invention concerne des procédés de traitement de tumeurs bénignes, précancéreuses ou non métastatiques utilisant un antagoniste spécifique anti-VEGF. L'invention concerne également des procédés de traitement d'un sujet risquant de développer des tumeurs bénignes, précancéreuses ou non métastatiques utilisant un antagoniste spécifique anti-VEGF. L'invention concerne également des procédés de traitement ou de prévention de la récurrence d'une tumeur en utilisant un antagoniste spécifique anti-VEGF ainsi que l'utilisation d'antagonistes spécifiques de VEGF dans une thérapie du cancer par néoadjuvant et adjuvant.

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