A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/138 (2006.01) A61K 47/14 (2006.01) A61K 47/38 (2006.01) A61P 5/32 (2006.01) A61P 15/00 (2006.01)
Patent
CA 2559748
The present invention provides methods for treating and preventing benign breast disease by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogenic effect. In patients with benign breast disease, this effect induces disease regression. In patients at risk for developing breast cancer, the anti-estrogenic effect prevents formation of benign breast conditions that can lead to cancer.
La présente invention concerne des méthodes de traitement et de prévention d'un cancer du sein bénin par administration à une patiente de 4-hydroxy tamoxifène. Lors de son administration percutanée au niveau des seins d'une patiente, 4-hydroxy tamoxifène se concentre localement et exerce un effet anti-oestrogénique. Chez des patients souffrant d'une maladie du sein, cet effet induit une régression de la maladie. Chez des patients présentant un risque de développer un cancer du sein, l'effet anti-oestrogénique prévient la formation de dérèglements bénins du sein qui peuvent déboucher sur un cancer.
Fetherstonhaugh & Co.
Laboratoires Besins International
Laboratories Besins International
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