Enhanced systemic absorption of intradermally delivered...

A - Human Necessities – 61 – M

Patent

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A61M 5/158 (2006.01) A61K 9/70 (2006.01) A61K 31/395 (2006.01) A61K 31/727 (2006.01) A61K 38/19 (2006.01) A61K 38/27 (2006.01) A61K 38/28 (2006.01) A61M 37/00 (2006.01) A61N 1/30 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2450354

A method for administration of a substance into the dermis of a mammal is disclosed. The method involves administration into the dermis by injection which results in improved systemic absorption relative to that obtained upon subcutaneous administration of the substance. The substance administered may be a growth hormone, alow molecular weight heparin or a dopamine receptor agonist.

Procédé servant à administrer une substance dans le derme d'un mammifère. Ce procédé consiste à effectuer l'administration dans le derme par injection, ce qui permet d'obtenir une absorption systémique améliorée par rapport à une administration sous-cutanée de la substance. Cette dernière peut être une hormone de croissance, héparine de poids moléculaire bas ou un agoniste du récepteur de dopamine.

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