Peptide antagonists of zonulin and methods for use of the same

Details Peptide antagonists of zonulin and methods for use of the same Peptide antagonists of zonulin and methods for use of the same

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2338005

Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the opening of mammalian tight junctions.

Cette invention, qui a trait à des antagonistes peptidiques, concerne également des techniques d'utilisation de ceux-ci. Ces antagonistes peptidiques se fixent au récepteur de zonula occludens sans pour autant moduler physiologiquement l'ouverture de jonctions serrées mammaliennes.

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