C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61P 35/00 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C12N 15/63 (2006.01) G01N 33/534 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2403242
The present invention provides binding moieties for CEA, which have a variety of uses wherever detecting, isolating or localizing CEA, and particularly CEA as opposed to cross-reactive antigens such as NCA, is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding CEA, which is overexpressed in adenocarcinomas of endodermally derived digestive system epithelia and fetal colon. Such polypeptides and disclosed derivatives are useful, e.g., as imaging agents for CEA-expressing tumors.
L'invention concerne des fractions de liaison ~ ACE qui comportent diverses applications dans la d~tection, l'isolement ou la localisation d'ACE ; en particulier, l'utilisation de ces fractions est avantageuse par rapport ~ des antignes ~ r~action crois~e tels que NCA (antigne non sp~cifique ~ r~action crois~e). L'invention concerne notamment des polypeptides synth~tiques isol~s capables de se lier ~ ACE, qui est surexprim~ dans les ad~nocarcinomes de l'~pith~lium du systme digestif et du cÙlon foetal d'origine endodermique. Ces polypeptides et les d~riv~s d~crits sont utiles, p. ex. comme agents d'imagerie pour des tumeurs exprimant ACE.
Ladner Robert Charles
Rondon Isaac Jesus
Dyax Corp.
Smart & Biggar
LandOfFree
Binding peptides for carcinoembryonic antigen (cea) does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Binding peptides for carcinoembryonic antigen (cea), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Binding peptides for carcinoembryonic antigen (cea) will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2048542