Divided dose therapies with vascular damaging activity

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/661 (2006.01) A61K 31/66 (2006.01) A61K 33/24 (2006.01) A61K 41/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2402078

The invention concerns the use of a vascular damaging agent or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for administration in divided doses for use in the production of a vascular damaging effect in a warm-blooded animal such as a human. In particular the vascular damaging agent is ZD6126, or a pharmaceutically acceptable salt thereof. The invention also relates to methods of treatment using a vascular damaging agent in divided doses.

L'invention concerne l'utilisation d'un agent de dégradation vasculaire ou d'un sel de celui-ci acceptable d'un point de vue pharmaceutique dans la fabrication d'un médicament destiné à être administré en doses fractionnées et destiné à générer un effet de dégradation vasculaire chez un être à sang chaud tel qu'un être humain. L'agent de dégradation vasculaire est notamment ZD6126 ou un sel de celui-ci acceptable d'un point de vue pharmaceutique. L'invention concerne également des procédés de traitement utilisant un agent de dégradation vasculaire en doses fractionnées.

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